Related Experiment Video

Updated: Jun 15, 2025

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Letter to the editors regarding "Inter-laboratory validation of bioaccessibility testing for metals" by Henderson et

P E Rasmussen1, P Huntsman2, T M Singer3

  • 1Environmental and Radiation Health Sciences Directorate, Health Canada, Ottawa, Canada; Department of Earth and Environmental Science, University of Ottawa, Ottawa, Canada.

Regulatory Toxicology and Pharmacology : RTP
|August 23, 2024
PubMed
Abstract

No abstract available in PubMed .

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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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