Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stages of General Anesthesia01:22

Stages of General Anesthesia

391
Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
391
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

66
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
66
Depolarizing Blockers: Pharmocokinetics01:19

Depolarizing Blockers: Pharmocokinetics

315
Depolarizing blockers are administered through intravenous injection. Succinylcholine is the most common choice of depolarizing blockers in emergency clinical practices. Although they have a rapid onset, they readily diffuse away from the motor end plate into the extracellular fluid. They are metabolized by enzymes such as liver butyrylcholinesterase and plasma pseudocholinesterases. This produces a short duration of action, typically 5-10 minutes long, unlike nondepolarizing blockers, which...
315
  1. Home
  3. Effect Of Mannitol On Postoperative Delirium In Patients Undergoing Coronary Artery Bypass Graft: A Randomised Controlled Trial.
  1. Home
  3. Effect Of Mannitol On Postoperative Delirium In Patients Undergoing Coronary Artery Bypass Graft: A Randomised Controlled Trial.

Related Experiment Video

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
07:46

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia

Published on: May 9, 2013

29.1K

Effect of mannitol on postoperative delirium in patients undergoing coronary artery bypass graft: a randomised

Masumeh Hemmati Maslakpak1, Sohrab Negargar2, Ali Farbod3

  • 1Maternal and Childhood Obesity Research Center, Nursing and Midwifery School, Urmia University of Medical Sciences, Urmia, Iran (the Islamic Republic of).

Open Heart
|August 23, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

Adding mannitol to cardiopulmonary bypass prime solution significantly reduced postoperative delirium in cardiac surgery patients. This intervention offers a promising strategy for improving patient outcomes after coronary artery bypass surgery.

Keywords:
Cardiac Surgical ProceduresCoronary Artery BypassHeart, Artificial

More Related Videos

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
09:12

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery

Published on: March 27, 2018

9.4K
A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
04:38

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

10.2K

Related Experiment Videos

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
07:46

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia

Published on: May 9, 2013

29.1K
Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
09:12

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery

Published on: March 27, 2018

9.4K
A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
04:38

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

10.2K

Area of Science:

  • Cardiology
  • Anesthesiology
  • Neurosurgery

Background:

  • Postoperative delirium (POD) is a common complication after cardiac surgery with cardiopulmonary bypass (CPB).
  • POD increases adverse effects, hospital stay, mortality, and healthcare costs.
  • Preventing POD is crucial for improving patient recovery and reducing healthcare burdens.

Purpose of the Study:

  • To evaluate the efficacy of mannitol in the CPB prime solution for preventing POD in patients undergoing coronary artery bypass surgery.
  • To assess the impact of mannitol on the incidence of POD.
  • To investigate secondary outcomes including ventilation duration, ICU stay, and mortality.

Main Methods:

  • A single-center, double-blinded, randomized controlled trial was conducted from December 2022 to May 2023.
  • Patients aged 18-70 undergoing elective coronary artery bypass surgery were included.
  • The intervention group (n=45) received 200 mL mannitol in the CPB prime solution, while the control group (n=45) received Ringer's lactate.

    • Main Results:

    • The incidence of POD was significantly lower in the mannitol group (22.25%) compared to the control group (42.2%) (p=0.035).
    • No significant differences were observed in demographic characteristics, CPB time, aortic cross-clamp time, mechanical ventilation duration, ICU length of stay, mortality, or return to the operating room.
    • Mannitol administration did not affect key surgical or perioperative parameters.

    Conclusions:

    • Adding mannitol to the CPB prime solution is an effective strategy for reducing the incidence of POD after cardiac surgery.
    • This intervention shows potential for improving patient outcomes and reducing complications associated with cardiac procedures.
    • Further research may explore optimal mannitol dosage and its long-term effects.