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Updated: Jun 15, 2025

Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens
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Pseudomyxoma peritonei peritonitis

Pranathi Yannamani1, Lillian Chungu2, Rajesh Shetty2

  • 1Wye Valley NHS Trust, Hereford, Herefordshire, UK pranathiyannamani@gmail.com.

BMJ Case Reports
|August 23, 2024
PubMed

Insights

Pseudomyxoma peritonei (PMP) is a rare condition causing gelatinous ascites, often from appendiceal tumors. Early diagnosis and surgical management are crucial for this malignancy risk.

Area of Science:

  • Gastroenterology
  • Oncology
  • Surgical Pathology

Background:

  • Pseudomyxoma peritonei (PMP) is a rare neoplastic condition characterized by mucinous ascites.
  • It typically originates from mucin-producing appendiceal tumors, necessitating prompt recognition and specialist care due to malignancy potential.

Purpose of the Study:

  • To present a case of Pseudomyxoma peritonei (PMP) arising from a ruptured appendix.
  • To highlight the importance of prompt diagnosis and surgical intervention in managing PMP.

Main Methods:

  • A diagnostic laparoscopy was performed on a male patient presenting with acute abdominal pain.
  • Extensive intra-abdominal mucin was identified and removed.
  • A laparoscopic appendectomy was conducted.

Main Results:

  • Histopathology confirmed Pseudomyxoma peritonei (PMP) originating from a ruptured appendix.
  • The patient's presentation included right iliac fossa peritonism and elevated inflammatory markers.

Conclusions:

  • Pseudomyxoma peritonei (PMP) can present acutely and mimic other abdominal pathologies.
  • Laparoscopic appendectomy and mucin washout are key management steps for PMP originating from the appendix.
Keywords:
Gastrointestinal surgeryGeneral surgerySurgical oncology

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