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Updated: Jun 15, 2025

Measuring and Modeling Contractile Drying in Human Stratum Corneum
Published on: March 1, 2017
Age-related variations in stratum corneum hydration in the foot
Esther Chicharro-Luna1, Sara Zúnica-García2, Cynthia Martinez-Algarra2
1Department of Behavioural Sciences and Health, Nursing Area, Faculty of Medicine, Miguel Hernández University, Institute of Health and Biomedical Research of Alicante (ISABIAL), Ctra N332, km 87, CP. 03550 San Juan de Alicante, Alicante, Spain.
Objective:
The aims of the study are to identify which region of the foot has lower hydration according to age, measure the variation in the level of stratum corneum hydration of the foot across the a wide age range, and examine hydration differences of the foot according to gender.
Study Design:
A descriptive observational study was conducted to assess stratum corneum hydration of the foot among 504 participants recruited between November 2023 and March 2024.
Main Outcomes Measures:
Stratum corneum hydration assessment was conducted using a Corneometer 825® probe at 10 specific points on the foot. Data on sociodemographic variables, medical history, foot care habits, and hydration-related factors were collected. Statistical analyses were performed using SPSS v. 24.0.
Results:
Stratum corneum hydration of the foot varied significantly across regions, with higher hydration in the digital zone and lower hydration in the heel. An inverse correlation was found between age and hydration, with younger participants exhibiting higher hydration levels. Women showed higher hydration than men. Differences in hydration were observed between the right and left feet.
Conclusion:
This study highlights the importance of localized assessment of foot skin dehydration. Aging significantly affects stratum corneum hydration of the foot. Gender differences in hydration suggest the importance of personalized approaches to skin care. Differential hydration between feet underscores the influence of mechanical load.
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