Application of selenium to reduce heavy metal(loid)s in plants based on meta-analysis

Agricultural soils are currently at risk of pollution from toxic heavy metal(loid)s (HMs) due to human activities, resulting in the excessive accumulation of arsenic (As), cadmium (Cd), chromium (Cr), copper (Cu), iron (Fe), mercury (Hg), manganese (Mn), lead (Pb) and zinc (Zn) in food plants. This poses significant risks to human health. Exogenous selenium (Se) has been proposed as a potential solution to reduce HMs accumulation in plants. However, there is currently a lack of comprehensive quantitative overview regarding its influence on the accumulation of HMs in plants. This study utilized meta-analysis to consolidate the existing knowledge on the impact of Se amendments on plant HMs accumulation from contaminated soil media. The present study conducted a comprehensive meta-analysis on literature published prior to December 2023, investigating the effects of different factors on HMs accumulation by meta-subgroup analysis and meta-regression model. Se application showed an inhibitory effect on plant uptake of Hg (28.9%), Cr (25.5%), Cd (25.2%), Pb (22.0%), As (18.3%) and Cu (6.00%) concentration. There was a significant difference in the levels of HMs between treatments with Se application and those without Se application in various plant organs. The percentage changes in the HMs contents of the organs varied from -13.0% to -22.0%. Compared with alkaline soil (pH > 8), Se application can reduce more HMs contents in plants in acidic soil (pH < 5.5) and neutral soil (pH = 5.5-8). For daily food plants(e.g. rice, wheat and corn), Se application can reduce HMs contents in Oryza sp., Triticum sp. and Zea sp., ranging from 14.0-20.0%. Our study emphasizes that the impact of Se on reducing HMs depends on the single or combined effects of Se concentration, plant organs, plant genera and soil pH condition.