Genetics and Genomics 101
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Updated: Jun 15, 2025

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
Published on: August 15, 2019
1Department of Animal Science, University of Tennessee, 2506 River Drive, Knoxville, TN 37996, USA; Department Large Animal Clinical Sciences, University of Tennessee, Knoxville, TN, USA.
Abstract:
Genetic mutations, both favorable and unfavorable, are the raw material for improvement in livestock populations. The random inheritance of these mutations is essential for generating progenies with genetic potential greater than their parents. These mutations can act either in a simple manner, such that a single alteration disrupts phenotype, or in a complex manner where hundreds or thousands of mutations of small effect create a continuous distribution of phenotypes. Selection tools leverage phenotypic records, pedigrees, and genomics to estimate the genetic potential of individual animals. This more accurate accounting of genetic potential has generated enormous gains in livestock populations.
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