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Updated: Jun 15, 2025

Accuracy in Dental Medicine, A New Way to Measure Trueness and Precision

Accuracy in Dental Medicine, A New Way to Measure Trueness and Precision

Published on: April 29, 2014

Assessing transparency practices in dental randomized controlled trials.

Mayara Colpo Prado¹, Lara Dotto², Bernardo Agostini¹

¹Graduate Program in Dentistry, ATITUS Educação, Passo Fundo, RS, Brazil.

BMC Medical Research Methodology

|August 24, 2024

Summary

Transparency in dental randomized controlled trials (RCTs) is low, especially for data sharing. Protocol registration varies, while conflict of interest and funding disclosures are common. Promoting transparency is vital for evidence-based dentistry.

Keywords:

Dentistry Meta-research Randomized controlled trial Research report

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Area of Science:

Dental Research
Clinical Trials
Meta-Research

Background:

Transparency is crucial for the integrity of scientific research.
Randomized controlled trials (RCTs) are fundamental to evidence-based dentistry.
Evaluating current transparency practices in dental RCTs is essential.

Purpose of the Study:

To assess the extent of transparency practices in published dental randomized controlled trials (RCTs).
To identify reporting patterns of key transparency elements across different dental specialties and geographical regions.

Main Methods:

A meta-research study analyzing RCTs in dentistry published in English between 2016 and 2021.
Systematic search of PubMed database.
Duplicate screening and data extraction focusing on protocol registration, data/code sharing, conflict of interest, and funding disclosures.

Main Results:

Out of 844 RCTs, only 12.86% reported data/code sharing, while 50.36% reported protocol registration.
Conflict of interest (83.41%) and funding (71.68%) declarations were widely reported.
Data sharing and protocol registration showed significant variability globally and across specialties, unlike conflict of interest and funding.

Conclusions:

Adherence to transparent scientific standards, including protocol registration and data/code sharing, needs significant improvement in dental research.
Promoting consistent reporting of transparency elements is critical for advancing evidence-based dentistry.
Active engagement from researchers and institutions is necessary to foster a culture of transparency.