Related Experiment Video
Updated: May 5, 2026
14:49
Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration
Published on: September 29, 2018
41.9K
Xanthoma combining osteonecrosis in knee joint: a case report
Hai Su1, Yichen Gong1, Lei Chen1
1The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang Province, 310053, China.
BMC Musculoskeletal Disorders
|August 24, 2024
Summary
This case study details a rare instance of knee joint osteonecrosis with synovial xanthoma. Arthroscopic excision of the xanthoma effectively relieved pain and improved mobility in the patient.
Area of Science:
- Orthopedics
- Rheumatology
- Pathology
Background:
- Xanthoma commonly affects subcutaneous tissues; joint involvement is rare.
- Knee joint osteonecrosis combined with xanthoma presents a unique clinical challenge.
Observation:
- A 50-year-old female presented with knee joint pain and limited mobility due to osteonecrosis.
- Initial conventional treatment for osteonecrosis yielded no significant improvement.
- Synovial xanthoma was identified within the affected knee joint.
Findings:
- The patient underwent arthroscopic excision of the knee joint synovial xanthoma.
- Post-procedure, Visual Analog Scale (VAS) pain scores improved from 7 to 2.
- Knee joint mobility increased from 10-103° to 10-140°.
Implications:
- Arthroscopic excision of synovial xanthoma offers a viable treatment for this rare condition.
- This case provides a potential therapeutic strategy for similar future presentations.
- Successful management highlights the importance of considering xanthoma in refractory knee joint osteonecrosis.
