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Transcription01:10

Transcription

146.8K
Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
146.8K
Gene-Environment Interactions01:20

Gene-Environment Interactions

270
Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
270

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Updated: Jun 15, 2025

Analyzing Gene Expression from Marine Microbial Communities using Environmental Transcriptomics
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Analyzing Gene Expression from Marine Microbial Communities using Environmental Transcriptomics

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Environmental community transcriptomics: strategies and struggles.

Jeanet Mante1, Kyra E Groover2, Randi M Pullen3

  • 1Oak Ridge Associated Universities, Oak Ridge, 37831, TN, USA.

Briefings in Functional Genomics
|August 25, 2024
PubMed
Summary
This summary is machine-generated.

Community transcriptomics analyzes RNA transcripts in environmental samples to understand organism interactions. This review explores advances in transcriptomic techniques and their application to overcome community transcriptomics challenges.

Keywords:
label-free cell sortingmetatranscriptomicssingle cell transcriptomicsspatial transcriptomicstranscriptomics

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Area of Science:

  • Molecular Biology
  • Ecology
  • Bioinformatics

Background:

  • Transcriptomics studies RNA transcripts to reveal gene expression and cellular mechanisms.
  • Community transcriptomics extends this to environmental microbial communities, exploring inter-organism interactions.
  • Analyzing diverse environmental RNA samples presents significant extraction and analysis challenges.

Purpose of the Study:

  • To review recent advancements in transcriptomic techniques.
  • To assess the applicability and viability of these techniques for community transcriptomics.
  • To identify potential solutions for current hurdles in the field.

Main Methods:

  • Literature review of transcriptomic methodologies.
  • Assessment of RNA extraction protocols for diverse environmental samples.
  • Evaluation of bioinformatic analysis pipelines for community transcriptomic data (e.g., read mapping, de novo assembly).

Main Results:

  • Recent advances offer improved RNA extraction efficiency and quality from complex samples.
  • Newer bioinformatic tools enhance the accuracy of mapping and assembly for community transcriptomic data.
  • Several techniques show promise for overcoming existing challenges in the field.

Conclusions:

  • Advances in transcriptomics are making community transcriptomics more feasible.
  • Further development in extraction and analysis methods is crucial for robust community transcriptomic studies.
  • This field holds significant potential for understanding complex environmental interactions.