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Related Experiment Videos

Streptococcal bacteremia in hepatobiliary operations.

J I Blenkharn, L H Blumgart

    Surgery, Gynecology & Obstetrics
    |February 1, 1985
    PubMed
    Summary
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    Fecal streptococci are common in bile infections and resistant to standard prophylactic antibiotics. This study highlights their significant role in bacteremia among patients with obstructive jaundice.

    Area of Science:

    • Microbiology
    • Infectious Diseases
    • Surgical Infections

    Background:

    • Fecal streptococci are frequently isolated from bile cultures.
    • Aminoglycoside and cephalosporin antibiotics are commonly used for biliary tract surgical prophylaxis.
    • These antibiotics exhibit limited efficacy against fecal streptococci.

    Purpose of the Study:

    • To investigate the incidence and clinical significance of fecal streptococci in biliary tract infections.
    • To evaluate the role of fecal streptococci in bacteremia associated with obstructive jaundice.
    • To consider alternative prophylactic antibiotic strategies.

    Main Methods:

    • Retrospective analysis of positive bile cultures over a defined period.
    • Identification and susceptibility testing of isolated microorganisms.

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  • Review of patient records for episodes of bacteremia and clinical outcomes.

    • Main Results:

    • Fecal streptococci accounted for 5-15% of all positive bile cultures.
    • Fifteen out of 64 (23%) bacteremia episodes in obstructive jaundice patients were caused by fecal streptococci.
    • Observed resistance of fecal streptococci to commonly used prophylactic antibiotics.

    Conclusions:

    • Fecal streptococci represent a significant pathogen in biliary tract infections, particularly in obstructive jaundice.
    • Current prophylactic antibiotic regimens may be inadequate due to resistance patterns.
    • Acylureidopenicillin antibiotics warrant consideration for prophylaxis in at-risk patient populations.