Related Experiment Video

Updated: Jun 15, 2025

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
11:20

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

3.7K

Iatrogenic macular hole following PFCL injection: Implications of retinal dimpling as an intraoperative indicator

Aditya Kelkar1, Mounika Bolisetty1, Sukanya Mondal1

  • 1National Institute of Ophthalmology, Pune, India.

American Journal of Ophthalmology Case Reports
|August 26, 2024
PubMed
Abstract

Insights

Perfluorocarbon liquid injection during retinal detachment surgery can cause macular holes. Careful technique is crucial to prevent this rare complication and ensure successful patient outcomes.

Area of Science:

  • Ophthalmology
  • Vitreoretinal Surgery

Background:

  • Perfluorocarbon liquids (PFCLs) are vital in managing retinal detachment (RD).
  • Unique risks exist, including subretinal migration.
  • Macular hole (MH) formation during PFCL injection is an underreported complication.

Observation:

  • A localized retinal dimpling occurred during PFCL jet stream injection in a rhegmatogenous RD case.
  • This dimpling was immediately followed by MH formation and subretinal PFCL migration.
  • Internal limiting membrane peeling and PFCL mobilization were performed.

Findings:

  • The case demonstrates a novel complication of PFCL injection: induced macular hole.
  • Successful management involved surgical intervention to close the MH and remove subretinal PFCL.
  • Post-operative OCT confirmed MH closure and vision improvement.

Implications:

  • Highlights the need for meticulous PFCL injection techniques to avoid iatrogenic trauma.
  • Emphasizes understanding the mechanism of PFCL-induced MH for improved surgical strategies.
  • Underscores the importance of prompt management of PFCL-related complications in retinal surgery.
Keywords:
Macular holePerfluorocarbon liquidRetinal detachmentRetinal dimpling

More Related Videos

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats04:16

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Published on: March 7, 2025

282
Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation06:59

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

Published on: February 29, 2020

8.1K

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
528
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
454