Lactobacillus gasseri associated severe soft tissue infection of the lower extremity: A case report

Lactobacilli are gram-positive, lactic acid-producing, facultative anaerobes of the human microbiota located in the human gastrointestinal tract, genitourinary tract, and the oral cavity and are considered non-pathogenic. When certain risk factors are present, they have the potential to cause serious infections. The incidence of localized infections associated with Lactobacilli are rare and to our knowledge we present the first known case of severe soft tissue infection of the extremity linked to a Lactobacillus strain.

We describe the case of a 41-year-old man with a history of type 2 Diabetes Mellitus (DM), arterial hypertension and schizophrenia, who was admitted for weakness, high fever of 39.7 °C (103.5°F) and an abscess formation of the left thigh caused by an infection with Lactobacillus gasseri (L.gasseri).

While infections caused by Lactobacilli are rare, it is crucial not to underestimate the potential of typically non-pathogenic bacteria like L. gasseri to act as infectious agents in immunocompromised patients. Abscess drainage and antibiotic treatment were successful treatment strategies for this rare case of soft tissue infection cause by L.gasseri.