Related Experiment Video
Updated: Jun 15, 2025
06:55
Protocol to Create Chronic Wounds in Diabetic Mice
Published on: September 25, 2019
20.2K
A Case of Recurrent Diabetic Foot Ulcers With Multi-drug Resistant Poly-Microbial Infections.
Radha Kunjalwar1, Aditya S Pedaprolu2, Akshunna Keerti3
1Microbiology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus
|August 26, 2024
Summary
Diabetic foot ulcers (DFUs) pose severe risks, including amputation. This case highlights challenges in treating recurrent DFUs caused by resistant gram-negative bacteria, emphasizing the need for advanced therapeutic strategies.
Area of Science:
- Diabetology
- Infectious Diseases
- Wound Care
Background:
- Diabetic foot ulcers (DFUs) are a significant complication of diabetes mellitus.
- Recurrent DFUs can lead to severe outcomes, including amputation.
Observation:
- A 40-year-old male with type II diabetes presented with recurrent DFUs and toe necrosis.
- The patient underwent surgical intervention and antimicrobial therapy with persistent infection and graft failure.
Findings:
- Gram-negative bacteria, resistant to common treatments, were identified in the diabetic foot infections.
- Polymicrobial infections correlated with the severity of the diabetic foot infection.
Implications:
- This case underscores the complexity of managing DFUs, particularly those with resistant pathogens.
- Effective treatment strategies for recurrent DFUs require addressing polymicrobial infections and antimicrobial resistance.
Keywords:
amputationdiabetes mellitusdiabetic foot infectionsdiabetic foot ulcermulti-drug resistant infection
