An Infant With Kawasaki Disease: A Case Report and Literature Review

Yifan Ren1

  • 1Department of Paediatrics, Shaoxing Keqiao Women and Children's Hospital, Shaoxing, CHN.

Cureus
|August 26, 2024
PubMed

Insights

Kawasaki disease (KD) can affect even very young infants, leading to serious heart complications. Early diagnosis and treatment with IVIG and aspirin are crucial for preventing coronary artery abnormalities.

Area of Science:

  • Pediatric Cardiology
  • Infectious Diseases

Background:

  • Kawasaki disease (KD) is a primary cause of acquired heart disease in children.
  • Delayed treatment increases the risk of coronary artery (CA) abnormalities, myocardial ischemia, infarction, and mortality.
  • Younger age is a significant risk factor for developing severe CA aneurysms in KD patients.

Observation:

  • A 1.5-month-old infant presented with fever and elevated inflammatory markers, initially unresponsive to ceftriaxone.
  • The infant developed classic KD symptoms including rash, palm/sole induration, BCG site reaction, cracked lips, and conjunctival hyperemia.
  • Diagnosis of complete Kawasaki disease was made based on clinical presentation.

Findings:

  • Intravenous immunoglobulin (IVIG) and aspirin were administered on the third day of fever.
  • Follow-up assessments at 1, 3, 6, and 12 months post-discharge showed normal cardiac findings.
  • The infant showed a complete recovery without coronary artery complications.

Implications:

  • This case highlights that infants under 6 months can present with complete Kawasaki disease.
  • Early recognition and prompt treatment are essential to prevent severe cardiovascular sequelae in young infants.
  • Aggressive management can lead to favorable outcomes, preventing long-term cardiac damage.

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