Related Experiment Video
Updated: May 6, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
An Infant With Kawasaki Disease: A Case Report and Literature Review
1Department of Paediatrics, Shaoxing Keqiao Women and Children's Hospital, Shaoxing, CHN.
Insights
Kawasaki disease (KD) can affect even very young infants, leading to serious heart complications. Early diagnosis and treatment with IVIG and aspirin are crucial for preventing coronary artery abnormalities.
Area of Science:
- Pediatric Cardiology
- Infectious Diseases
Background:
- Kawasaki disease (KD) is a primary cause of acquired heart disease in children.
- Delayed treatment increases the risk of coronary artery (CA) abnormalities, myocardial ischemia, infarction, and mortality.
- Younger age is a significant risk factor for developing severe CA aneurysms in KD patients.
Observation:
- A 1.5-month-old infant presented with fever and elevated inflammatory markers, initially unresponsive to ceftriaxone.
- The infant developed classic KD symptoms including rash, palm/sole induration, BCG site reaction, cracked lips, and conjunctival hyperemia.
- Diagnosis of complete Kawasaki disease was made based on clinical presentation.
Findings:
- Intravenous immunoglobulin (IVIG) and aspirin were administered on the third day of fever.
- Follow-up assessments at 1, 3, 6, and 12 months post-discharge showed normal cardiac findings.
- The infant showed a complete recovery without coronary artery complications.
Implications:
- This case highlights that infants under 6 months can present with complete Kawasaki disease.
- Early recognition and prompt treatment are essential to prevent severe cardiovascular sequelae in young infants.
- Aggressive management can lead to favorable outcomes, preventing long-term cardiac damage.
Abstract:
Kawasaki disease (KD) is the leading cause of acquired heart disease in children in developed countries. Delayed treatment can lead to coronary artery (CA) abnormalities, potentially causing myocardial ischemia, infarction, and death. Younger age is a risk factor for developing bilateral large CA aneurysms in KD patients. A one-and-a-half-month-old infant presented with fever and elevated inflammatory markers. Post-admission ceftriaxone injections were ineffective. Subsequently, the patient experienced recurrent high fevers, accompanied by rashes, erythema, and induration of the palms and soles, erythema, swelling at the Bacillus Calmette-Guerin (BCG) scar site, cracked lips, and conjunctival hyperemia, all of which were indicative of KD. Intravenous immunoglobulin (IVIG) and aspirin were administered on the third day of fever. Follow-ups at one, three, six, and 12 months post discharge revealed normal findings. This case demonstrates that even very young infants can develop complete KD, and early treatment can prevent CA complications.
More Related Videos
05:51Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
Published on: July 24, 2016
06:15Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Rheumatic Heart Disease I: Introduction
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Rheumatic Heart Disease IV: Nursing Management
Acute Kidney Injury IV: Diagnostic Studies and Prevention