Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Genomics

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Severe acute limb ischemia in patients with COVID-19: A single-center case series.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2026

Same author

Recent advances in tendon redox biology: the interplay of oxidative stress, calcium signaling, and antioxidant defence mechanisms.

Frontiers in pharmacology·2026

Same author

Retraction Note: Post-COVID reactivation of latent Bartonella henselae infection: a case report and literature review.

BMC infectious diseases·2026

Same author

Chronic osteomyelitis of the right thumb caused by Actinomyces radingae and Finegoldia magna: a case report and literature review.

BMC infectious diseases·2026

Same author

Cutaneous Squamous Cell Carcinoma with Hypercalcemia of Malignancy and Skeletal Metastasis: Perioperative Case Report of Above-Knee Amputation.

Journal of visualized experiments : JoVE·2026

Same author

Osteoarthritis: multitissue pathology, molecular mechanisms, clinical management, and emerging precision and regenerative therapies.

Frontiers in pharmacology·2026

Search research articles

Related Experiment Video

Updated: Jun 15, 2025

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Published on: July 6, 2022

Advances in spatial multi-omics in tumors.

Junyan Wang¹, Ahmad Alhaskawi², Yanzhao Dong²

¹The First Affiliated Hospital, Zhejiang University, Hangzhou, China.

|August 26, 2024

Summary

This summary is machine-generated.

Spatial multi-omics reveal tumor ecosystem heterogeneity, improving cancer therapies. These advanced techniques map cellular interactions and microenvironments, paving the way for better treatments like immunotherapy.

Keywords:

biomarkers immunotherapy spatial multi-omics targeted therapies tumor ecosystem tumor microenvironment

More Related Videos

Visualization, Quantification, and Mapping of Immune Cell Populations in the Tumor Microenvironment

Visualization, Quantification, and Mapping of Immune Cell Populations in the Tumor Microenvironment

Published on: March 25, 2020

Digital Spatial Profiling for Characterization of the Microenvironment in Adult-Type Diffusely Infiltrating Glioma

Digital Spatial Profiling for Characterization of the Microenvironment in Adult-Type Diffusely Infiltrating Glioma

Published on: September 13, 2022

Related Experiment Videos

Last Updated: Jun 15, 2025

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Published on: July 6, 2022

Visualization, Quantification, and Mapping of Immune Cell Populations in the Tumor Microenvironment

Visualization, Quantification, and Mapping of Immune Cell Populations in the Tumor Microenvironment

Published on: March 25, 2020

Digital Spatial Profiling for Characterization of the Microenvironment in Adult-Type Diffusely Infiltrating Glioma

Digital Spatial Profiling for Characterization of the Microenvironment in Adult-Type Diffusely Infiltrating Glioma

Published on: September 13, 2022

Area of Science:

Oncology
Genomics
Systems Biology

Background:

Single-cell techniques show genetic and transcriptional diversity within tumors.
Spatial organization and microenvironment heterogeneity remain underexplored.
Understanding the tumor ecosystem is crucial for effective cancer treatment.

Purpose of the Study:

To review emerging spatial omics technologies in cancer research.
To discuss the therapeutic applications of spatial multi-omics.
To propose future directions for spatial omics in oncology.

Main Methods:

Review of current literature on spatial multi-omics techniques.
Analysis of how these techniques reveal tumor spatial heterogeneity.
Examination of impacts on classical and novel cancer therapies.

Main Results:

Spatial multi-omics provide unprecedented insights into tumor ecosystems.
These technologies elucidate cellular interactions and microenvironment characteristics.
Spatial data can enhance surgical, radiotherapeutic, and chemotherapeutic strategies.

Conclusions:

Spatial omics are transforming cancer research and therapy.
Understanding spatial heterogeneity is key to improving treatment outcomes.
Future developments promise even more sophisticated applications in precision oncology.