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Updated: Jun 15, 2025
Establishment of the Dual Humanized TK-NOG Mouse Model for HIV-associated Liver Pathogenesis
Published on: September 11, 2019
Kidney transplant recipient with history of HIV, HBV, and past HCV infection
José Ignacio Cerrillos-Gutiérrez1, Ricardo Parra-Guerra1,2, Alfredo Gutiérrez-Govea3,4
1Nephrology and Transplantation Division, UMAE, National Medical Center of the West, Mexican Institute of Social Security, Guadalajara, Mexico.
Abstract:
Chronic viral infections caused by the human immunodeficiency virus (HIV), hepatitis C (HCV), and hepatitis B (HBV) are common among patients with end-stage renal disease (ESKD). These infections were once considered contraindications to kidney transplantation due to potential risks associated with long-term immunosuppression. Improved management and antiviral therapies have changed the prognosis and survival of this group of patients, along with an increased experience in transplanting people with these viral infections. We report the first successful kidney transplant in an ESKD patient on hemodialysis with a history of concomitant HIV, HCV and HBV infection in Mexico.
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