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Choroid Plexitis and Obstructive Hydrocephalus Secondary to Cryptococcal Meningoencephalitis in an Immunocompetent

Antonio Santana Veliz1, Nneka F Onwumere2, Amar Swarnkar3

  • 1Diagnostic Radiology, Upstate University Hospital, Syracuse, USA.

Cureus
|August 27, 2024
PubMed

Insights

Cryptococcus fungus rarely invades the choroid plexus, even in healthy individuals. This case highlights rare bilateral choroid plexus invasion causing obstructive hydrocephalus in an immunocompetent patient.

Area of Science:

  • Medical Mycology
  • Neuroimaging
  • Infectious Diseases

Background:

  • Cryptococcus is an opportunistic fungus
  • Typically affects immunocompromised individuals
  • Choroid plexus invasion by Cryptococcus is uncommon

Observation:

  • A previously healthy male presented with symptoms
  • Radiologic imaging revealed bilateral choroid plexus abnormalities
  • Obstructive hydrocephalus was diagnosed

Findings:

  • Confirmed bilateral choroid plexus invasion by Cryptococcus
  • Demonstrated radiologic evidence of fungal infiltration
  • Correlated imaging findings with clinical presentation of hydrocephalus

Implications:

  • Expands understanding of Cryptococcus tropism
  • Highlights rare presentations in immunocompetent hosts
  • Emphasizes the importance of neuroimaging in diagnosing CNS fungal infections
Keywords:
choroid plexitischoroid plexitis hydrocephalus casechoroid plexitis imagingchoroid plexitis in cryptococcosiscryptococcal meningitis neuroimagingcryptococcal meningoencephalitisfungal infection in immunocompetentimmunocompetent cryptococcal meningitismri findings choroid plexitisneuroimaging cryptococcal infection

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