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Updated: Jun 15, 2025

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Published on: March 11, 2016
Sonographic findings using the SAFE-A protocol in pre- and post-hemodialysis patients
Matheus Rabahi1, Maria Goretti Polito2, Larissa Louise Cândida Pereira Takaoka3
1Departamento de Medicina Interna, Hospital Estadual Alberto Rassi, Goiânia, GO, Brazil. matheusrabahi@gmail.com.
Background:
Accurate assessment of relative intravascular volume is one of the cornerstones for the proper management of hospitalized patients requiring hemodialysis. Currently, the use of dynamic parameters such as bedside ultrasonography is recommended to support the assessment of the intravascular volume profile. This study aimed to prospectively evaluate findings of sonographic assessment of intravascular volume estimate (SAFE-A) protocol among hemodialysis inpatients with end-stage renal disease, before and after the hemodialysis sessions, and correlate these findings with the net ultrafiltrate (UFNET).
Results:
A positive correlation was found between the negative variation of 1 point in the score of the SAFE-A protocol with the withdrawal of 426.73 mL of net ultrafiltrate.
Conclusions:
There was a strong correlation between the score of the SAFE-A protocol and the net ultrafiltrate. Therefore, this study concludes that the application of the SAFE-A protocol in dialysis patients demonstrates a correlation between the suggested score and volume status, consistent with findings from the original study conducted in a distinct population.
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