Related Experiment Video
Updated: Jun 15, 2025

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting
Published on: November 30, 2015
The link between traumatic experiences and health in late life: challenges and opportunities for US-based
Audrey R Murchland1, Karestan C Koenen1,2,3,4, Eleanor Hayes-Larson5
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
Abstract:
Trauma, defined as exposure to actual or threatened death, serious injury, or sexual violence, is a pervasive, major public health challenge that disproportionately burdens socially disadvantaged groups and has known consequences for health outcomes in early and midlife. Despite plausible mechanisms by which trauma may also be a critically important risk factor for health outcomes in late life, there is presently a lack of literature evaluating the consequences of trauma on aging-related health outcomes and inequities, such as dementia. In this commentary, we (1) discuss drivers of the paucity of epidemiologic evidence on trauma and health outcomes in late life, namely a lack of available data, supported by detailed review of trauma measures, including interpersonal violence-a particularly common form of trauma-in 7 established longitudinal aging cohort studies in the United States; (2) address 4 common concerns about the inclusion of trauma measures in cohort studies; and (3) suggest ways forward, including specific assessment tools to measure interpersonal violence after a structured review of the PhenX Toolkit, to facilitate critical research to understand the impact of trauma on outcomes in late life.
Related Concept Videos
Longitudinal Research
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Longitudinal Studies
Introduction to Stress and Lifestyle
Traumatic Memory
Cognitive Development During Adulthood

