Related Experiment Video
Updated: Jun 15, 2025

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Association between quantity and quality of carbohydrate intake and glaucoma: a cross-sectional study from the NHANES
Fang Li1, Yinu Ma2, Yingying Tang2
1Department of Ophthalmology, The First Affiliated Hospital of Xinjiang Medical University, 137 Liyushan South Road, Urumqi, 830054, Xinjiang Uygur Autonomous Region, China. fangli_oph@outlook.com.
Background:
Glaucoma is a public health problem among the worldwide population. Dietary as a modifiable factor have been reported to be associated with glaucoma. This study aimed to explore the association between quantity and quality of carbohydrate (CH) intake and glaucoma among U.S. adults.
Methods:
In this cross-sectional study, data of participants aged ≥ 40 years old were extracted from the National Health and Nutrition Examination Survey (NHANES) 2005-2008. CH intake information were obtained by 24-h dietary recall interview. Glaucoma was defined by regraded disc images. Covariates included demographic information, physical examination, laboratory values, complications and nutrients intake. The weighted univariable and multivariate logistic regression models were used to assess the association between the quantity and quality of CH intake and glaucoma. Subgroup analyses based on the history of hypertension were further assessed the association.
Results:
The weighted population included a total of 4789 participants, of whom 119 (2.48%) had glaucoma. After adjusting for age, adrenal cortical steroids, hypertension, chronic kidney diseases, diabetes and energy intake, high quantity (OR = 1.83, 95%CI: 1.08-3.11) and low quality (OR = 0.44, 95CI%: 0.20-0.98) of CH intake were associated with the higher odds of glaucoma. High quantity of CH intake (OR = 2.06, 95%CI: 1.15-3.69) was associated with the high odds of glaucoma in hypertension, while high quality of CH intake (fiber-to-CH ratio: OR = 0.23, 95%CI: 0.06-0.82; CH-to-fiber and fiber-to-added sugars ratio: OR = 0.10, 95%CI: 0.02-0.53) were associated with the lower odds of glaucoma in participants without hypertension.
Conclusion:
In NAHNES 2005-2008, higher quantity and lower quality CH intake were associated with the high odds of glaucoma, especially among patients without hypertension. This study provides a theoretical basis for the health management of glaucoma patients from the perspective of dietary intake.
More Related Videos
07:22Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
Published on: March 7, 2025
13:47Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
Published on: June 3, 2018
Related Concept Videos
Glaucoma: Overview
Overview of Carbohydrate Metabolism
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
Carbohydrates: Dietary Sources and Requirements
Glucose Absorption Into the Small Intestine
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment