Oriented Synthesis of Glycine from CO₂, N₂, and H₂O via a Cascade Process

Air contains carbon, hydrogen, oxygen, and nitrogen elements that are essential for the constitution of amino acids. Converting the air into amino acids, powered with renewable electricity, provides a green and sustainable alternative to petrochemical-based methods that produce waste and pollution. Here, taking glycine as an example, we demonstrated the complete production chain for electrorefining amino acids directly from CO₂, N₂, and H₂O. Such a prospective Scheme was composed of three modules, linked by a spontaneous C-N bond formation process. The high-purity bridging intermediates, separated from the stepwise synthesis, boosted both the carbon selectivity from CO₂ to glycine of 91.7 % and nitrogen selectivity from N₂ to glycine of 98.7 %. Under the optimum condition, we obtained glycine with a partial current density of 160.8 mA cm^-2. The high-purity solid glycine product was acquired with a separation efficiency of 98.4 %. This work unveils a green and sustainable method for the abiotic creation of amino acids from the air components.