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Enhancing linkage to care for hepatitis B, D, and C patients: A retrospective-prospective study
Elena Vargas-Accarino1,2, Ariadna Rando-Segura3, Adriana Palom2,4
1Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.
Insights
A strategy successfully reintegrated 47.2% of viral hepatitis patients into care. This initiative aimed to connect individuals diagnosed with hepatitis B, D, or C to essential medical management and reduce fatalities.
Area of Science:
- Hepatology
- Public Health
- Infectious Diseases
Background:
- The World Health Organization (WHO) targets a 65% reduction in viral hepatitis fatalities by 2030.
- Viral hepatitis, including hepatitis B, D, and C, remains a significant global health concern.
Purpose of the Study:
- To identify and re-engage all diagnosed individuals with hepatitis B, D, or C into appropriate medical care.
- To investigate reasons for the lack of linkage to care among diagnosed patients.
Main Methods:
- A retrospective-prospective search was conducted in a central laboratory database for patients with hepatitis B, D, or C virus (HBV, HDV, HCV) infection.
- Patient records were reviewed, and individuals were contacted to offer specialist medical visits for reintegration into care.
Main Results:
- Out of 3731 viral hepatitis patients, 644 (37%) with HBV, 20 (29%) with HDV, and 1116 (56%) with HCV were not linked to care.
- A linkage strategy successfully reintegrated 64% of HBV, 100% of HDV, and 27% of HCV patients into care.
- 35.8% of patients requiring linkage had moved or lacked contact data, highlighting logistical challenges.
Conclusions:
- The implemented linkage strategy successfully reintegrated a significant proportion of eligible viral hepatitis patients into care.
- Overall, 47.2% of eligible patients were linked to care, demonstrating the strategy's effectiveness in improving patient management.
- Addressing barriers such as patient relocation and incomplete data is crucial for optimizing care linkage in viral hepatitis management.
Background:
The WHO has set a goal to decrease viral hepatitis-related fatalities by 65% by 2030.
Aims:
To locate and retrieve to care all individuals diagnosed with hepatitis B, D or C, and investigate why they were not linked to appropriate medical management.
Methods:
We conducted a retrospective-prospective search for patients with hepatitis B, D or C virus (HBV, HDV and HCV) infection in the central laboratory database of the Barcelona northern health area (catchment population, 450,000). We reviewed records and contacted candidates for retrieval who were offered a specialist medical visit.
Results:
We reviewed records of 3731 patients with viral hepatitis (January 2019-December 2022): 1763 HBsAg+, 69 anti-HDV+ and 1899 HCV-RNA+. Among these, 644 (37%) HBV, 20 (29%) HDV and 1116 (56%) HCV patients were not currently linked to care. The proportion of patients receiving appropriate care was higher in HBV and HDV (p < 0.0001), and a higher percentage of unlinked hepatitis C patients had low life expectancy/comorbidities (39%; p < 0.0001). After implementing the linkage strategy, 254 HBV, 16 HDV and 54 HCV patients were successfully reintegrated into care. Among 1780 patients requiring linkage, 638 (35.8%) had moved to another health area or were missing essential contact data.
Conclusions:
Among patients with viral hepatitis who required appropriate specialist care and were eligible for contact, 64% with HBV, 100% with HDV and 27% with HCV were successfully reintegrated into care. Overall, 324 (47.2%) eligible patients were linked to care, indicating the success of this strategy.
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