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Updated: Jun 15, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

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Quality of life in persons with mild cognitive impairment: a systematic review and meta-analysis

Priya Gopalakrishnan1, Shivani Tiwari1, Ravishankar Nagaraja2

  • 1Manipal Academy of Higher Education, Manipal College of Health Professions, Department of Speech and Hearing, Manipal, Karnataka, India.

Dementia & Neuropsychologia
|August 28, 2024
PubMed

Insights

Older adults with mild cognitive impairment (MCI) may experience a lower quality of life (QOL) compared to healthy peers. Further research is needed to develop specific QOL assessment tools for this population.

Area of Science:

  • Gerontology
  • Neurology
  • Public Health

Background:

  • Global aging population increases concerns about age-related cognitive conditions like dementia and mild cognitive impairment (MCI).
  • Mild cognitive impairment (MCI) involves cognitive deficits exceeding age and literacy expectations, potentially impacting quality of life (QOL).

Purpose of the Study:

  • To systematically review and compare the QOL of older adults with and without MCI.
  • To conduct a meta-analysis to quantitatively assess QOL differences between these groups.

Main Methods:

  • Comprehensive literature search across major databases (PubMed, Scopus, Web of Science, etc.) up to May 2021.
  • Inclusion of 23 articles for systematic review and 12 for meta-analysis.
  • Quality assessment of included studies using the Modified Downs and Black tool.

Main Results:

  • Most studies indicated QOL differences between older adults with MCI and healthy controls.
  • Meta-analysis revealed that older adults with MCI had lower QOL scores, though the difference was not statistically significant.
  • The Modified Downs and Black tool was used to assess study quality.

Conclusions:

  • Older adults with MCI may experience diminished QOL compared to their healthy counterparts.
  • Future research should prioritize developing tailored QOL assessment tools for individuals with MCI.
  • Longitudinal studies are recommended to track cognitive changes and QOL in this demographic.
Keywords:
AgedCognitive DysfunctionMeta-analysisQuality of LifeSystematic Review

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