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The health and economic burden of breathlessness, Australia, 2019: a national survey
Anthony P Sunjaya1,2, Leanne M Poulos3, Gian Luca Di Tanna1,4
1The George Institute for Global Health, Sydney, NSW.
Objective:
To examine the impact of breathlessness on quality of life, health care use, productivity loss, and economic costs in Australia.
Study Design:
National internet-based survey of Australian adults drawn from a web-based survey panel (National Breathlessness Survey).
Participants, Setting:
Australian adults (18 years or older), nationally representative by age group, gender, state of residence, and postcode-based socio-economic status (Index of Relative Socioeconomic Disadvantage quintile), 13-30 October 2019.
Main Outcome Measures:
Quality of life assessed with the EQ-5D 5-level version (EQ-5D-5L) and visual analogue scale (EQ-VAS), health care use, productivity loss, and societal cost, each by severity of breathlessness (modified Medical Research Council [mMRC] dyspnoea scale; mMRC grade 1: mild breathlessness; mMRC grades 2-4: clinically important breathlessness).
Results:
Of 10 072 adults who completed the survey, mild breathlessness was reported by 3044 respondents (30.2%), and clinically important breathlessness by 961 (9.5%). The mean EQ-VAS score was 74.8 points (95% confidence interval [CI], 74.3-75.3 points) and the mean EQ-5D-5L score 0.846 (95% CI, 0.841-0.850) for respondents with mMRC grade 0 breathlessness; for each measure, the mean value declined with increasing severity of breathlessness (trends: each P < 0.001). Respondents with clinically important breathlessness were more likely than those with mild breathlessness to report non-urgent general practitioner visits, urgent general practitioner visits, and specialist visits (exception: mMRC scores of 4) during the preceding year. Among the 2839 respondents of working age, the likelihood of being employed declined with increasing breathlessness severity (mMRC grades 4 v 1: adjusted odds ratio, 0.34; 95% CI, 0.22-0.53). Adjusted mean annual societal cost per person was $1413 (95% CI, $1326-1501) for respondents with mMRC grade 1 breathlessness, $2065 (95% CI, $1766-2365) at mMRC grade 2, $1795 (95% CI, $1371-2218) at mMRC grade 3, and $2075 (95% CI, $1389-2762) at mMRC grade 4.
Conclusion:
Breathlessness imposes major burdens on individuals, the health care system, and the economy.
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