Oxidative Stress and Erectile Dysfunction: Pathophysiology, Impacts, and Potential Treatments

Aris Kaltsas1, Athanasios Zikopoulos2, Fotios Dimitriadis3

  • 1Third Department of Urology, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, 12462 Athens, Greece.

Summary

Oxidative stress (OS) significantly contributes to erectile dysfunction (ED) by impairing nitric oxide (NO) signaling and endothelial function. Managing OS through antioxidants and lifestyle changes may improve ED symptoms and quality of life.

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