Related Experiment Video
Updated: May 22, 2026
07:41
A Neurite Outgrowth Assay and Neurotoxicity Assessment with Human Neural Progenitor Cell-Derived Neurons
Published on: August 6, 2020
7.5K
NeuroQuantify - An image analysis software for detection and quantification of neuron cells and neurite lengths using
Ka My Dang1, Yi Jia Zhang2, Tianchen Zhang2
1Max Planck Institute of Microstructure Physics, Weinberg 2, Halle D-06120, Germany; Max Planck-University of Toronto Centre for Neural Science and Technology, Canada.
Journal of Neuroscience Methods
|August 28, 2024
Summary
NeuroQuantify is a new open-source software that uses deep learning for fast and accurate segmentation of cells and neurites in neuronal network images. This tool aids in quantifying neuron growth and network development for research.
Area of Science:
- Neuroscience
- Biotechnology
- Image Analysis
Background:
- Accurate segmentation of cells and neurites in neuronal network microscopy images is crucial for quantitative analysis of neuron growth and differentiation.
- This analysis provides insights into neuronal structures, essential for studying neurodegenerative diseases and pharmaceutical effects.
Purpose of the Study:
- To develop an efficient and accurate open-source software for segmenting cells and neurites in phase contrast microscopy images of neuronal networks.
Main Methods:
- Development of NeuroQuantify, an open-source software utilizing deep learning for image segmentation.
- The software processes phase contrast microscopy images to analyze neuronal structures.
Main Results:
- NeuroQuantify enables automatic detection and segmentation of cells and neurites.
- It provides quantitative measurements of neurite length and identification of neurite orientations.
- The software overcomes limitations of existing methods for automatic neuronal structure analysis.
Conclusions:
- NeuroQuantify offers a valuable, user-friendly tool for rapid and effective assessment of neuronal network development.
- The software is freely available for download on GitHub, promoting wider research accessibility.
More Related Videos
Related Concept Videos
01:29Pulmonary Tuberculosis I
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
01:28Pulmonary Tuberculosis II
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
01:31Pulmonary Tuberculosis III
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
01:26Pulmonary Tuberculosis IV
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
01:28Pulmonary Tuberculosis V
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...