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Left Ventricular Assist Devices in Latin America: Current Landscape and Future Directions

Paola Morejón Barragán1, Christian Guilliod2, Lucrecia M Burgos3

  • 1Heart Failure Department, Clinica Guayaquil, Guayas, Ecuador.

Journal of Cardiac Failure
|August 28, 2024
PubMed
Abstract

No abstract available in PubMed .

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Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
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