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IgDK multiple myeloma presenting as unilateral proptosis
Summary
A rare case of IgDK multiple myeloma presented as a destructive middle cranial fossa tumor causing painful proptosis. Radiotherapy yielded satisfactory results for this elderly patient.
Area of Science:
- Oncology
- Neurology
- Ophthalmology
Background:
- Multiple myeloma is a plasma cell malignancy that can rarely manifest with extramedullary disease.
- Destructive cranial tumors are uncommon presentations of multiple myeloma.
Observation:
- A 72-year-old female presented with painful proptosis and a destructive middle cranial fossa tumor.
- Initial evaluation suggested a neoplastic process involving the skull base and orbit.
Findings:
- Histopathologic and immunologic studies of a biopsy confirmed IgDK multiple myeloma.
- Biochemistry and bone marrow examination corroborated the diagnosis of IgDK multiple myeloma.
Implications:
- This case highlights the importance of considering multiple myeloma in the differential diagnosis of destructive cranial masses.
- Early diagnosis and appropriate treatment, such as radiotherapy, can lead to favorable outcomes even in rare presentations.