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A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Association between the Behavioral Activation Mechanism and Depression Severity: Focusing on Avoidance Patterns of
Koki Takagaki1, Satoshi Yokoyama2
1Health Service Center, Hiroshima University, 1-7-1 Kagamiyama, Higashihiroshima 739-8514, Japan.
Abstract:
Subthreshold depression is a risk factor for depression among university students. Positive environmental reinforcement is a significant mediator of avoidance and depression in healthy university students. However, this relationship is understudied in those with subthreshold depression or depression. Therefore, this study examined these associations in healthy university students and those who fit the criteria for subthreshold depression or depression. We conducted an online survey with 1200 undergraduate students (600 women and 600 men, mean age = 20.61, SD = 1.59). The results revealed significant differences in avoidance patterns (behavioral social, behavioral nonsocial, cognitive social, and cognitive nonsocial), with participants with depression presenting the highest scores. The results of the mediation analysis were similar to those of previous studies in healthy groups. However, in the subthreshold-depression group, positive environmental reinforcement was mediated by behavioral social and behavioral non-social avoidance and depressive symptoms. In the group with depression, positive environmental reinforcement was mediated only by behavioral nonsocial avoidance and depressive symptoms. Associations between avoidance patterns, positive environmental reinforcement, and depressive symptoms vary with the degree of depressive symptoms. The results revealed by this study provide new foundational insights to prevent subthreshold depression among university students from deteriorating into depression.
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