Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

8.2K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
8.2K
Olfaction01:25

Olfaction

44.3K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
44.3K
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

9.1K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
9.1K
Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

2.4K
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
2.4K
Physiology of Emotion01:20

Physiology of Emotion

675
The physiology of emotions is a multifaceted process involving the autonomic nervous system, brain structures, hormones, and neurotransmitters. This intricate interplay dictates how emotions manifest in the body and influence behavior.
Autonomic Nervous System
The autonomic nervous system (ANS) plays a critical role in emotional responses by regulating involuntary physiological functions. It consists of two main components: the sympathetic and parasympathetic systems. The sympathetic system...
675
Neural Regulation01:37

Neural Regulation

39.2K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

COPA syndrome unmasked by anti-neutrophil cytoplasmic antibody-positive immune-complex nephritis.

Kidney international·2026
Same author

Use of Infliximab in Infantile Kawasaki Disease: Experiences over 8 Years.

Indian pediatrics·2025
Same author

Authorship dynamics: a bibliometric analysis of low- and middle-income country author representation in high-impact dermatology journals.

The British journal of dermatology·2025
Same author

Targeting Spinal Interneurons for Respiratory Recovery After Spinal Cord Injury.

Cells·2025
Same author

Effects of short-term isolation on social behaviors in prairie voles.

PloS one·2024
Same author

Increased ambient outdoor temperatures are associated with increased disease flaring in hidradenitis suppurativa.

Archives of dermatological research·2023

Related Experiment Video

Updated: Jun 14, 2025

A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation
10:42

A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation

Published on: August 18, 2014

8.9K

Aggression Unleashed: Neural Circuits from Scent to Brain.

Rhea Singh1, Kyle Gobrogge2

  • 1The Mortimer B. Zuckerman Mind Brain Behavior Institute, Department of Neuroscience, Columbia University, New York, NY 10027, USA.

Brain Sciences
|August 29, 2024
PubMed
Summary

This review explores the neural circuits controlling aggression in rodents, focusing on olfactory cues and brain regions. Understanding these pathways is key to developing new therapies for aggression disorders.

Keywords:
aggressionmedial amygdala (MeA)prefrontal cortexrodentsventral premammillary nucleus (PMv)ventromedial hypothalamus (VMHvl)

More Related Videos

Constructing an Olfactometer for Rodent Olfactory Behavior Studies Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling
08:36

Constructing an Olfactometer for Rodent Olfactory Behavior Studies Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling

Published on: April 11, 2025

186
In-depth Physiological Analysis of Defined Cell Populations in Acute Tissue Slices of the Mouse Vomeronasal Organ
10:11

In-depth Physiological Analysis of Defined Cell Populations in Acute Tissue Slices of the Mouse Vomeronasal Organ

Published on: September 10, 2016

7.6K

Related Experiment Videos

Last Updated: Jun 14, 2025

A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation
10:42

A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation

Published on: August 18, 2014

8.9K
Constructing an Olfactometer for Rodent Olfactory Behavior Studies Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling
08:36

Constructing an Olfactometer for Rodent Olfactory Behavior Studies Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling

Published on: April 11, 2025

186
In-depth Physiological Analysis of Defined Cell Populations in Acute Tissue Slices of the Mouse Vomeronasal Organ
10:11

In-depth Physiological Analysis of Defined Cell Populations in Acute Tissue Slices of the Mouse Vomeronasal Organ

Published on: September 10, 2016

7.6K

Area of Science:

  • Neuroscience
  • Behavioral Biology

Background:

  • Aggression is vital for survival but its dysregulation causes significant human burden.
  • Past research faced limitations in neural circuit resolution, hindering understanding of aggression mechanisms.

Purpose of the Study:

  • To review aggression-provoking stimuli and detection, focusing on rodent olfactory systems.
  • To examine core aggression regions, their interactions, and prefrontal cortex connections.
  • To discuss cognitive control's role in regulating aggression and potential therapeutic interventions.

Main Methods:

  • Review of recent advancements in optogenetics, pharmacogenetics, single-cell RNA sequencing, and in vivo electrophysiology.
  • Analysis of rodent aggression circuitry, including olfactory pathways and prefrontal cortex integration.
  • Exploration of cognitive control mechanisms and therapeutic strategies.

Main Results:

  • Recent technological advances offer new insights into the neural basis of aggression.
  • Specific neural pathways and brain regions involved in aggression have been identified.
  • The role of the prefrontal cortex in modulating aggression is increasingly understood.

Conclusions:

  • A focused understanding of rodent aggression circuitry provides a foundation for novel therapeutic strategies.
  • Targeting specific neural pathways offers potential for treating aggression disorders.
  • Further research into cognitive control mechanisms can inform clinical interventions.