Toward Fully Automated Personalized Orthopedic Treatments: Innovations and Interdisciplinary Gaps

Area of Science:

• Orthopedic Surgery
• Biomedical Engineering
• Regenerative Medicine

Background:

• Personalized orthopedic devices offer enhanced long-term treatment success.
• Seamless integration and automation of personalized orthopedic treatments face challenges.
• Current clinical practices have limitations in achieving full personalization.

Purpose of the Study:

• Identify interdisciplinary gaps in integrating and automating advanced technologies for personalized orthopedic treatment.
• Explore innovations contributing to personalized orthopedic care.
• Propose strategies to bridge identified gaps.

Main Methods:

• Review of standard orthopedic clinical practices.
• Exploration of innovations: AI, biomaterials, genomics, lab-on-a-chip, medical imaging, biomechanical modeling, biomimicry, 3D printing, bioprinting, and implantable sensors.
• Analysis of interdisciplinary gaps and proposed solutions.

Main Results:

• Key findings emphasize the need for non-invasive bone quality assessment.
• Patient-specific biocompatibility and tailored device designs are critical.
• Integration of diverse technologies is essential for personalized orthopedic solutions.

Conclusions:

• Multidisciplinary collaboration is vital for advancing personalized orthopedic treatments.
• Automation of personalized orthopedic devices requires addressing interdisciplinary gaps.
• Transformative potential of integrated technologies for intelligent orthopedic systems.