Related Experiment Video

Updated: Jun 14, 2025

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
13:07

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Published on: January 15, 2022

3.8K

Clinical Updates in Coronary Artery Disease: A Comprehensive Review

Andrea Bottardi1, Guy F A Prado1,2, Mattia Lunardi1,3

  • 1Division of Cardiology, Cardio-Thoracic Department, University of Verona, 37100 Verona, Italy.

Journal of Clinical Medicine
|August 29, 2024
PubMed

Insights

Coronary artery disease (CAD) management requires updated strategies beyond current guidelines. This review synthesizes recent advancements in non-invasive diagnostics, risk assessment, and treatments for acute and stable CAD.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Clinical Practice

Background:

  • Coronary artery disease (CAD) remains a leading cause of mortality globally, despite advancements.
  • Current clinical guidelines may not fully incorporate the latest research findings.
  • There is a need to bridge the gap between emerging data and routine clinical practice.

Purpose of the Study:

  • To provide an updated overview of recent clinical developments in coronary artery disease (CAD).
  • To focus on non-invasive diagnostic techniques, risk stratification, and therapeutic interventions.
  • To offer insights beyond existing guidelines for healthcare providers.

Main Methods:

  • Comprehensive literature review of recent clinical updates in CAD.
  • Synthesis of novel data on diagnostic and therapeutic strategies.
  • Focus on both acute and stable coronary artery disease scenarios.

Main Results:

  • Recent advancements in non-invasive diagnostic modalities for CAD.
  • Updated approaches to risk stratification in patients with CAD.
  • Emerging medical and interventional therapies for acute and stable CAD.
  • Identification of data not yet integrated into current practice guidelines.

Conclusions:

  • Continuous integration of new evidence is crucial for optimal CAD management.
  • This review highlights key recent developments to inform clinical decision-making.
  • Adopting updated strategies can improve patient outcomes and healthcare system efficiency.

Keywords:
coronary artery bypass graftcoronary artery diseasecoronary computed tomography angiographydual antiplatelet therapyfraction flow reservepercutaneous coronary intervention

More Related Videos

Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders05:58

Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders

Published on: February 3, 2021

3.4K
Author Spotlight: Enhancing Coronary Artery Revascularization05:25

Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

659

Related Concept Videos

Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.2K
Cardiovascular Drugs: Classification based on Therapeutic Indications01:18

Cardiovascular Drugs: Classification based on Therapeutic Indications

Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...
2.1K
Coronary Circulation01:21

Coronary Circulation

The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
2.4K
Antianginal Drugs: Calcium Channel Blockers and Ranolazine01:25

Antianginal Drugs: Calcium Channel Blockers and Ranolazine

Angina pectoris, a primary symptom of ischemic heart disease, requires careful pharmacological interventions. In this context, calcium channel blockers (CCBs) and ranolazine have emerged as crucial pharmacotherapeutic agents, providing deep insights into the complexities of angina management.
CCBs, a diverse class that includes dihydropyridines (nifedipine) and diphenylalkylamines (verapamil and diltiazem), exert their effect by blocking calcium channels in cardiac and smooth muscle cells. This...
464
Overview of Systemic Arteries01:11

Overview of Systemic Arteries

The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the...
793
Antianginal Drugs: Nitrates and β-Blockers01:16

Antianginal Drugs: Nitrates and β-Blockers

In cardiovascular health, antianginal drugs combat angina pectoris — a condition marked by chest pain owing to diminished blood flow to the heart.
Organic nitrates,  such as nitroglycerin, play a pivotal role. Once metabolized, they liberate nitric oxide, a molecular marvel. Nitric oxide triggers guanylyl cyclase and augments cGMP production. This biochemical cascade orchestrates the relaxation of vascular smooth muscles, ushering in vasodilation and enhancing coronary blood flow....
547