Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hormonal Regulation01:33

Hormonal Regulation

33.0K
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
33.0K
Teratogenicity01:07

Teratogenicity

2.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Melatonin and Mitochondrial Redox Homeostasis in Reproduction: Mechanistic Links Between Circadian Signaling and Fertility Outcomes.

Biology·2026
Same author

Endometrial Microbiome Profiles in Women Evaluated for Infertility or Recurrent Miscarriage: A Single-Center Descriptive Study.

Diagnostics (Basel, Switzerland)·2026
Same author

The Microbiome-Mitochondria-Extracellular Vesicle Axis in HPV Persistence and Cervical Carcinogenesis.

Genes·2026
Same author

Management of Hereditary Hypofibrinogenemia During Pregnancy: A Scoping Review Towards Personalized Obstetric Care.

Journal of clinical medicine·2026
Same author

Psychological Experiences of Pregnancy Following Transplantation: A Systematic Qualitative Review.

Medicina (Kaunas, Lithuania)·2026
Same author

Epigenetics, Oxidative Stress, and the Microbiome in Endometriosis: Toward an Integrated Mechanistic Framework for Precision Medicine.

Journal of personalized medicine·2026

Related Experiment Video

Updated: Jun 14, 2025

Trophoblast Cell Recovery from Angiogenesis-Tube Formation Assay for Differentiation Marker Expression Analysis
05:30

Trophoblast Cell Recovery from Angiogenesis-Tube Formation Assay for Differentiation Marker Expression Analysis

Published on: November 8, 2024

378

Bridging the Gap between Galectin-3 Expression and Hypertensive Pregnancy Disorders: A Narrative Review.

Anastasios Potiris1, Alexandros Fotiou1, Eirini Drakaki2

  • 1Third Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.

Journal of Clinical Medicine
|August 29, 2024
PubMed
Summary

Galectin-3 (Gal-3) levels in pregnancy complications like preeclampsia show inconsistent results in placental tissue and maternal serum. Further research is needed to clarify Gal-3

Keywords:
Galectin-3 (Gal-3)HELLP syndromegestational hypertensionplacental insufficiencypreeclampsia

More Related Videos

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

778
High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo
06:43

High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo

Published on: November 8, 2018

10.2K

Related Experiment Videos

Last Updated: Jun 14, 2025

Trophoblast Cell Recovery from Angiogenesis-Tube Formation Assay for Differentiation Marker Expression Analysis
05:30

Trophoblast Cell Recovery from Angiogenesis-Tube Formation Assay for Differentiation Marker Expression Analysis

Published on: November 8, 2024

378
Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

778
High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo
06:43

High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo

Published on: November 8, 2018

10.2K

Area of Science:

  • Obstetrics and Gynecology
  • Immunology
  • Biochemistry

Background:

  • Preeclampsia and gestational hypertension are common pregnancy complications with unclear causes.
  • Galectin-3 (Gal-3), a glycan-binding protein, is implicated in pregnancy processes like placental development.
  • Understanding Gal-3's role could reveal new insights into preeclampsia pathogenesis.

Purpose of the Study:

  • To systematically review and synthesize existing research on Galectin-3 (Gal-3) in relation to preeclampsia and gestational hypertension.
  • To evaluate the consistency of findings regarding Gal-3 expression in placental tissue and maternal serum.

Main Methods:

  • A comprehensive literature search was conducted on Scopus and PubMed/MEDLINE databases until May 2024.
  • Eleven studies involving 1011 patients (453 preeclampsia, 558 controls) were included.
  • Data on Gal-3 expression in placental tissue, maternal serum, and umbilical cord blood were analyzed.

Main Results:

  • Inconsistent findings were reported for Gal-3 expression in placental tissue and maternal serum.
  • Five studies showed increased Gal-3 placental expression, while two found no difference or decreased expression.
  • Five studies reported increased maternal serum Gal-3 levels, while three found no significant difference.

Conclusions:

  • Galectin-3 (Gal-3) may play a role in preeclampsia pathogenesis, influenced by gestational age and placental insufficiency.
  • Current evidence is conflicting, necessitating further investigation.
  • Clarifying the correlation between Gal-3 and gestational hypertensive disorders is crucial.