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Diabetic Retinopathy

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

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Related Experiment Video

Updated: Jun 26, 2026

Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases

Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases

Published on: March 11, 2016

Fundus Autofluorescence in Diabetic Retinopathy.

Otilia-Maria Dumitrescu¹, Mihail Zemba^1,2, Daniel Constantin Brănișteanu³

¹Department of Ophthalmology, "Dr. Carol Davila" Central Military Emergency University Hospital, 010825 Bucharest, Romania.

Journal of Personalized Medicine

|August 29, 2024

Summary

Fundus autofluorescence is a valuable tool for evaluating diabetic retinopathy and diabetic macular edema. This non-invasive imaging technique helps detect damage and predict visual outcomes in patients.

Keywords:

diabetic macular oedema diabetic retinopathy fundus autofluorescence

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Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases

Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases

Published on: March 11, 2016

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Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

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Area of Science:

Ophthalmology
Medical Imaging

Background:

Diabetic retinopathy is a major cause of vision loss globally.
Fundus autofluorescence (FAF) is increasingly used in multimodal imaging for diabetic retinopathy (DR) and diabetic macular edema (DME).

Purpose of the Study:

To explore the role and significance of FAF in assessing diabetic retinopathy and diabetic macular edema.
To highlight FAF's utility in detecting retinal damage and predicting visual prognosis.

Main Methods:

Utilized short-wavelength autofluorescence (SWAF) and near-infrared autofluorescence (NIRF) techniques.
Correlated FAF findings with other imaging modalities and visual acuity.

Main Results:

SWAF in a cystoid pattern aids in detecting cystoid macular edema.
Increased SWAF and granular NIRF changes indicate photoreceptor and retinal pigment epithelium damage, correlating with reduced visual acuity.
Increased SWAF in DME is a prognostic factor for poor visual outcome, even post-fluid resolution.

Conclusions:

FAF is a rapid, non-invasive method for evaluating DME, retinal pigment epitheliopathy, and choroidopathy in diabetic patients.
FAF provides insights into DR pathophysiology and aids comprehensive patient evaluation.
FAF shows potential as a prognostic indicator for visual outcomes in diabetic retinopathy.