Comparison of Current International Guidelines on Premature Ejaculation: 2024 Update

Area of Science:

• Urology
• Sexual Medicine
• Clinical Guidelines

Background:

• Premature ejaculation (PE) is a prevalent male sexual dysfunction causing distress.
• Existing international guidelines offer varying perspectives on PE management.

Purpose of the Study:

• To compare current international guidelines on premature ejaculation (PE).
• To identify similarities and differences in definitions, classifications, and treatment recommendations.

Main Methods:

• Comparative analysis of guidelines from EAU, AUA/SMSNA, and ISSM.
• Assessment of guideline quality using the AGREE GRS.
• Examination of definitions, epidemiology, pathophysiology, diagnosis, and therapy.

Main Results:

• Significant variations exist in PE definitions and management recommendations across guidelines.
• EAU guidelines are most recent; AUA/SMSNA lack detail; ISSM is comprehensive but outdated.
• Guideline quality varied, with notable differences in scope and recency.

Conclusions:

• A unified definition and standardized diagnostic/therapeutic pathways for PE are crucial.
• Addressing inconsistencies in guidelines is essential for improving global PE patient management.