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Local Allergic Rhinitis-A Challenge for Allergology and Otorhinolaryngology Cooperation (Scoping Review)
Ovidiu Berghi1, Mihai Dumitru2, Romica Cergan3
1Allergology Department, Colentina Clinical Hospital, 020125 Bucharest, Romania.
Life (Basel, Switzerland)
|August 29, 2024
Summary
Local allergic rhinitis (LAR), a subtype of allergic rhinitis, is often misdiagnosed. This review covers diagnosis, quality of life, and treatments like immunotherapy for LAR.
Area of Science:
- Allergology
- Otorhinolaryngology
- Immunology
Background:
- Local allergic rhinitis (LAR) is a distinct subtype of allergic rhinitis (AR).
- It affects patients previously diagnosed with chronic non-allergic rhinitis.
- Symptoms include rhinorrhea, sneezing, and nasal itching triggered by allergens.
Purpose of the Study:
- To review current evidence on Local Allergic Rhinitis (LAR).
- To highlight diagnostic challenges and treatment options for LAR.
Main Methods:
- Scoping review of open-access PubMed literature.
- Analysis of diagnostic methods including nasal allergen challenge, local IgE, basophil activation test (BAT), and nasal cytology.
- Review of treatment strategies and quality of life impacts.
Main Results:
- Standard AR tests (skin prick, serum IgE) are often negative in LAR.
- Specialized tests are crucial for accurate LAR diagnosis.
- LAR significantly impacts quality of life, comparable to AR.
- Treatment options mirror AR: allergen avoidance, pharmacotherapy, and immunotherapy.
Conclusions:
- LAR requires specialized diagnostic approaches beyond standard allergy testing.
- Effective management strategies exist, including allergen immunotherapy.
- Further research is needed to address current limitations in diagnosis and treatment.
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