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Sleep Apnea

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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

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Obstructive Sleep Apnea after COVID-19: An Observational Study.

George-Cosmin Popovici^1,2, Costinela-Valerica Georgescu^3,4, Mihaela-Camelia Vasile^1,5

¹School for Doctoral Studies in Biomedical Sciences, "Dunarea de Jos" University from Galati, 800008 Galati, Romania.

Life (Basel, Switzerland)

|August 29, 2024

Summary

Hospitalized COVID-19 patients frequently develop severe obstructive sleep apnea (OSA). Risk factors include male gender, age over 60, obesity, and cardiovascular issues, necessitating further sleep disorder management strategies.

Keywords:

COVID-19 polygraphy sleep apnea

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Area of Science:

Pulmonology
Sleep Medicine
Infectious Diseases

Background:

Risk factors for severe COVID-19 and obstructive sleep apnea (OSA) share commonalities.
Post-COVID-19 complications, including sleep disorders, require further investigation.
Understanding the link between COVID-19 hospitalization and OSA is crucial for patient management.

Purpose of the Study:

To determine the prevalence of obstructive sleep apnea (OSA) in adult patients hospitalized for COVID-19 in southeastern Romania.
To identify associated factors contributing to the development of OSA post-COVID-19 hospitalization.
To inform clinical practice and future research directions for managing sleep disorders in post-COVID-19 patients.

Main Methods:

A follow-up study involving adult patients hospitalized for COVID-19 between 2021-2022.
Assessment of OSA using the Epworth and STOP-BANG questionnaires, alongside nocturnal polygraphy monitoring.
Evaluation conducted 12 weeks post-hospitalization for COVID-19.

Main Results:

Out of 331 patients, 257 were evaluated for sleep apnea.
A high prevalence of severe obstructive sleep apnea (OSA) was observed at 57.97%.
Significant associations identified include male gender, age >60, obesity, and cardiovascular comorbidities.

Conclusions:

Severe OSA is highly prevalent in patients hospitalized for COVID-19.
Male gender, older age, obesity, and cardiovascular comorbidities are key associated factors.
Recommendations include non-invasive ventilatory therapy (NIV) and lifestyle modifications; further strategies for diagnosis and monitoring are needed.