Advances in Aptamer-Based Biosensors for the Detection of Foodborne Mycotoxins

Yangyang Li ¹, Dan Zhang ², Xiaoyuan Zeng ¹

⁰Chongqing Key Laboratory for New Chemical Materials of Shale Gas, College of Chemistry and Chemical Engineering, Yangtze Normal University, Fuling, Chongqing 408100, China.

Molecules (basel, Switzerland) +

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August 29, 2024

View abstract on PubMed

Summary

Foodborne mycotoxins (FBMTs) pose a public health threat. Aptamer biosensors offer a promising, rapid, and sensitive alternative to traditional methods for detecting these toxins in food.

Area Of Science

Food Science
Analytical Chemistry
Biotechnology

Background

Foodborne mycotoxins (FBMTs) present significant risks to public health and food security.
Conventional detection methods for FBMTs are often complex, time-consuming, and expensive, hindering widespread application.
Aptamer-based biosensors have emerged as a powerful alternative for food safety monitoring.

Purpose Of The Study

To review recent advancements in aptamer-based biosensors for detecting foodborne mycotoxins.
To discuss the progress in both single-mode and dual-mode aptasensor designs and applications.
To identify current challenges and suggest future directions for developing user-friendly and rapid toxin detection systems.

Main Methods

Literature review focusing on aptasensor development for mycotoxin detection.
Analysis of recent research in single-mode and dual-mode aptasensor strategies.
Evaluation of device applications and performance metrics for aptasensors.

Main Results

Aptasensors demonstrate high affinity, specificity, and rapid response for FBMT detection.
Significant progress has been made in both single-mode and dual-mode aptasensor technologies.
Current strategies still face challenges in terms of operational simplicity and detection speed.

Conclusions

Aptamer biosensors are a viable and advancing technology for the sensitive and rapid detection of foodborne mycotoxins.
Further development is needed to overcome limitations and facilitate the transition towards practical, field-deployable toxin detection systems.
Future research should focus on enhancing ease of use and speed for improved food safety monitoring.

Keywords:

aptamer dual-mode biosensor foodborne mycotoxins