Related Experiment Video

Updated: Jun 14, 2025

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
05:53

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates

Published on: July 6, 2013

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Burden of Congenital CMV Infection: A Narrative Review and Implications for Public Health Interventions

Cecilia Liberati1, Giulia Sturniolo1, Giulia Brigadoi1

  • 1Department of Women's and Children's Health, Pediatric Infectious Disease, Padua University Hospital, 35126 Padua, Italy.

Viruses
|August 29, 2024
PubMed

Insights

Congenital Cytomegalovirus (CMV) is a common global infection. This review explores screening, treatment, and vaccines to reduce the burden of congenital CMV and its potential infant health impacts.

Area of Science:

  • * Infectious Diseases
  • * Public Health
  • * Pediatrics

Background:

  • * Congenital Cytomegalovirus (CMV) is the most prevalent congenital infection globally.
  • * Most infected infants are asymptomatic at birth, but some develop severe health issues like hearing loss or neurological impairment.
  • * Public health interventions are crucial for mitigating the impact of congenital CMV.

Purpose of the Study:

  • * To review maternal and neonatal screening programs for congenital Cytomegalovirus.
  • * To assess current evidence regarding treatment and vaccine development for CMV.
  • * To outline potential benefits and biases of public health interventions for congenital CMV.

Main Methods:

  • * Comprehensive literature review of studies on congenital Cytomegalovirus.
  • * Analysis of data on maternal and neonatal screening programs.
  • * Evaluation of evidence for CMV treatment and vaccine development.

Main Results:

  • * Congenital CMV infection presents a significant global health challenge with varied infant outcomes.
  • * Screening, treatment, and vaccine development are key areas for intervention.
  • * Evidence for the efficacy and optimal implementation of interventions requires ongoing evaluation.

Conclusions:

  • * Public health strategies, including screening, are essential to reduce the burden of congenital CMV.
  • * Further research into effective treatments and preventative vaccines is critical.
  • * Informed public health policy and debate require a thorough understanding of the evidence and potential intervention biases.

Keywords:
CMV awarenessCMV vaccinescytomegalovirusmaternal screeningneonatal screening

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