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Hepatitis B Prevalence and Referral Rates in Vulnerable Populations Undergoing Community-Based Screening-Results from

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|August 29, 2024
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Hepatitis B Virus (HBV) chronic infection prevalence in Romania was 1.67% in a large screening program. Key risk factors included male gender, specific age groups, rural Eastern location, low education, and history of medical procedures or unsafe contacts.

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hepatitis B virus (HBV)prevalencescreeningvulnerable population

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Area of Science:

  • Epidemiology
  • Public Health
  • Infectious Diseases

Background:

  • Hepatitis B Virus (HBV) poses a significant global health burden.
  • Chronic HBV infections lead to substantial morbidity and mortality worldwide.

Purpose of the Study:

  • To investigate the epidemiology, screening, and risk factors of HBV in Romania.
  • To analyze data from the national screening program, LIVE(RO)2.

Main Methods:

  • A national screening program, LIVE(RO)2, enrolled 320,000 individuals, predominantly from vulnerable populations.
  • Data on potential HBV transmission risk factors were collected via questionnaires.

Main Results:

  • The overall prevalence of chronic HBV infection was 1.67%, with regional variations.
  • Significant risk factors for HBsAg seropositivity included male gender, age 30-49 or 60-69, rural Eastern residence, lower education, and history of transfusions, surgeries, tattooing, hospitalizations, imprisonment, hemodialysis, unsafe sexual contact, or STIs.

Conclusions:

  • The study identified demographic and epidemiological patterns of HBV prevalence in Romania.
  • Socio-economic factors and specific lifestyle elements significantly modified HBV risk profiles, even in vulnerable groups.