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COVID19 Vaccination Considerations for Pregnant Women: A Systematic Review

Zahra Ghafari1, Amin Khameneh1, Leila Vahedi2

  • 1Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.

Iranian Journal of Nursing and Midwifery Research
|August 29, 2024
PubMed

Insights

Pregnant women face higher COVID-19 risks. While some studies lack data, most recommend COVID-19 vaccination for pregnant individuals to protect maternal and fetal health.

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Public Health

Background:

  • Pregnant women are at increased risk for severe outcomes from coronavirus disease 2019 (COVID-19).
  • This study addresses the critical question of COVID-19 vaccination recommendations for pregnant populations.
  • The research compares outcomes and considerations for pregnant versus non-pregnant women regarding COVID-19 vaccination.

Purpose of the Study:

  • To systematically review existing literature on COVID-19 vaccination in pregnancy.
  • To synthesize findings regarding the safety and efficacy of COVID-19 vaccines for pregnant women and their fetuses.
  • To inform clinical practice and public health policy on maternal immunization strategies.

Main Methods:

  • A systematic review was conducted using major scientific databases: PubMed, Embase, and Scopus.
  • Search terms included variations of COVID-19, SARS-CoV-2, pregnancy, and vaccination.
  • The review encompassed studies published between January 2020 and April 2022.

Main Results:

  • Out of 37 selected studies, 40.50% supported COVID-19 vaccination for pregnant women.
  • 24.30% of studies presented inconclusive findings on the topic.
  • 35.20% of studies opposed vaccination due to insufficient data.

Conclusions:

  • A significant portion of the literature recommends maternal immunization against COVID-19.
  • One-third of studies highlighted the need for clinical trials on COVID-19 vaccination outcomes in pregnant women.
  • The majority consensus leans towards recommending COVID-19 vaccines for pregnant individuals.
Abstract

Keywords:
COVID-19pregnancyvaccineswomen

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