Related Experiment Video
Updated: Jun 14, 2025

Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy
Published on: May 26, 2023
How to better prevent sudden cardiac death? Recent advances
Serena Bricoli1, Daniela Aschieri2, Giampaolo Niccoli3
1Ospedale Guglielmo da Saliceto Piacenza, Piacenza, Italy. serenabricoli@gmail.com
Abstract:
Sudden cardiac death (SCD) is a global public health problem. Despite efforts of the scientific community, it is characterized by low survival (<10%). Strategies used to prevent this catastrophic event are divided into those aimed at individual and populational level. Individuals known to be at a high risk for SCD may be treated with medications, implantable cardioverter‑defibrillators, catheter ablation, or temporary defibrillation devices. At the population level, efforts are concentrated on prevention of ischemic heart disease, as it is responsible for over 70% of sudden mortality cases in adults, and on development of resuscitation and early defibrillation programs. Much still needs to be done to improve survival by raising awareness in the population through training initiatives and by optimizing available technologies and making them more accessible.
Related Concept Videos
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Pulse rhythm
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

