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Endoscopic Response Reduces the Risk of Subsequent Pouchitis in Patients With Crohn's Disease-Like Pouch Inflammation
Maia Kayal1, Hannah Posner, Darwin Jimenez
1Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York, USA .
Introduction:
The aim of this study was to report the frequency and impact of endoscopic response and remission on the risk of subsequent pouchitis in patients with Crohn's disease-like pouch inflammation (CDLPI) on therapy.
Methods:
This was a single-center retrospective study of patients older than 18 years with CDLPI on therapy.
Results:
Among 110 included patients with CDLPI in clinical remission, endoscopic remission was not significantly associated with a reduced risk of subsequent pouchitis when compared with endoscopic response.
Discussion:
Endoscopic response, not remission, is sufficient to reduce the risk of subsequent pouchitis in patients with CDLPI.
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