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Updated: Jun 14, 2025

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro
Published on: April 8, 2020
Self-Assemblies of Carboxylic Acid Derivatives with Different Symmetry: Adjusting by Solvent and Guest Molecules
Shuai Wang1, Peng Lei2,3, Zhizhong Huang4
1College of Engineering, Shenyang Agricultural University, Shenyang 110866, China.
Abstract:
In this research, the self-assembly behaviors of two different symmetry carboxylic acid derivatives (HBTE and HBTE) regulated by solvent and guest molecule (coronene, COR) were explored at the liquid/solid interface by scanning tunneling microscopy, and the formation mechanism was investigated by density functional theory. In 1-phenyloctane, only HBTE molecules dissolved with extremely low concentration and self-assembled into a honeycomb structure and a new strip structure, while HBTE could not. In 1-heptanoic acid, HBTE and HBTE were easily dissolved, in which HBTE formed a regular row structure and HBTE formed a tetragonal structure, respectively. The host-guest interaction was investigated by introducing the COR molecules into their self-assembly structures, and due to the different symmetry, HBTE and HBTE displayed different accommodation behavior.
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