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Cryptococcal Osteomyelitis of the Patella: A Case Report
Jacob Harper1, Paul J Weatherby2, Mark A Foreman2
1John Sealy School of Medicine, The University of Texas Medical Branch, Galveston, Texas.
Case:
A 38-year-old woman presented to our clinic with right knee pain and difficulty ambulating. After cultures were obtained, a cryptococcal infection of the patella was identified. Subsequent workup revealed previously undiagnosed HIV/AIDS and a disseminated cryptococcal infection.
Conclusion:
Over a 20-month course, the patient was treated with fluconazole and antiretroviral therapy with very limited medication compliance. The disseminated infection caused cutaneous, hepatic, and cerebral complications. Eventually, compliance improved, and a final procedure to obtain post-treatment cultures and apply antifungal bone matrix was completed. The patient cleared the infection and will likely require lifetime antifungal treatment.
