Biopsychosocial predictors of rapid weight gain from birth to 6 months
Esther M Leerkes1, Cheryl Buehler1, Laurie Wideman2
1Department of Human Development and Family Studies, UNC Greensboro, Greensboro, North Carolina, USA.
Insights
Obesogenic feeding practices in early infancy significantly predict rapid weight gain in babies. Identifying and supporting families to reduce these behaviors is key to preventing childhood obesity.
Area of Science:
- Pediatrics
- Public Health
- Developmental Psychology
Background:
- Childhood obesity is a significant public health concern.
- Predictors of obesity risk in infancy require further identification.
- Understanding early life factors is crucial for prevention strategies.
Purpose of the Study:
- To investigate a biopsychosocial model predicting rapid weight gain (RWG) in the first six months of life.
- To identify key factors contributing to infant RWG.
- To explore the role of maternal and infant characteristics in early obesity development.
Main Methods:
- Recruited 299 pregnant women and their infants.
- Assessed maternal prenatal psychobiological risk (PPBR) including biomarkers and stress.
- Measured infant stress reactivity and maternal feeding practices and sensitivity at 2 and 6 months.
Main Results:
- Obesogenic feeding practices significantly predicted increased likelihood of RWG (β=0.30, p=0.01).
- Obesogenic feeding practices acted as an intervening mechanism, mediating the effect of PPBR on RWG (b=0.05, SE=0.04).
- This finding highlights the critical role of feeding behaviors in early infant weight gain.
Conclusions:
- Early identification of tendencies towards obesogenic feeding practices is vital.
- Interventions aimed at reducing obesogenic feeding behaviors can enhance childhood obesity prevention.
- Targeting feeding practices offers a promising avenue for early obesity prevention efforts.
Background:
Childhood obesity remains a public health crisis and identification of unique prenatal and early infancy predictors of obesity risk are critically needed.
Objectives:
We test a comprehensive biopsychosocial model of the predictors of rapid weight gain (RWG) in the first 6 months of life.
Methods:
Two hundred and ninety nine pregnant women and their infants participated. Maternal prenatal psychobiological risk (PPBR) was assessed during the third trimester via maternal anthropometrics, serum biomarkers (insulin, leptin, adiponectin), and maternal report of pregnancy complications, substance use, mental health and stress. Infant stress reactivity was measured at 2 months (cortisol output, resting RSA, observed irritability, negative emotionality). At 2 and 6 months, maternal self-report of obesogenic feeding practices and observed maternal sensitivity during three tasks were collected. RWG was classified based on change in weight-for-age z scores from birth to 6 months (>0.67 SD).
Results:
Obesogenic feeding practices predicted greater likelihood of RWG, β = 0.30, p = .0.01, independent of other predictors and covariates. Obesogenic feeding practices was the only proposed intervening mechanism that produced a significant indirect effect of PPBR on RWG, b = 0.05, S.E. = 0.04, 95% CI [0.002, 0.15], β = 0.06.
Conclusion:
Identifying proclivity towards obesogenic feeding practices and providing support to reduce these behaviours may enhance childhood obesity prevention efforts.
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