Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Isoflurane as a cost-effective alternative to sevoflurane for short-duration gynaecological brachytherapy: a randomised non-inferiority trial of emergence.

Journal of contemporary brachytherapy·2026
Same author

Diversity of electrocardiographic patterns in left main culprit acute ST-elevation myocardial infarction.

American heart journal·2025
Same author

Investigating the impact of milk protein, inulin, and honey on quality attributes of goat milk <i>yoghurt</i>.

Journal of food science and technology·2024
Same author

Association of Maternal Serum Homocysteine level with Maternal Birth Weight.

Mymensingh medical journal : MMJ·2024
Same author

Early integration of palliative care in cervical cancer: Experiences from a pilot study.

Journal of family medicine and primary care·2023
Same author

Low yield but high levels of multidrug resistance in urinary tract infections in a tertiary hospital, Nepal.

Public health action·2021
Same journal

Broad-Spectrum Antibiotics are Associated with worse Survival After Radical Treatment for Glioblastoma Multiforme: A Multicentre Study.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026
Same journal

Exploring the Need for Plan Adaptation in Robustly Optimised Head and Neck Intensity Modulated Proton Therapy: A Dosimetric Perspective From Initial Institutional Experience.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026
Same journal

Lifting the Lid on Best Practice in a Case of Oligometastatic Breast Cancer.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026
Same journal

Standardisation of Imaging Surveillance for Patients With Metastatic Melanoma Stopping Immune Checkpoint Inhibitors.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026
Same journal

Valuing Public Sector Data Assets: Methodological Perspectives From the Add-Aspirin Trial's Use of Healthcare Systems Data for Clinical Follow-Up.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026
Same journal

Autologous Cell Therapy in Oncology: Current Landscape and Future Directions.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026
See all related articles

Related Experiment Video

Updated: Jun 14, 2025

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.1K

Three-Dimensional Conformal Radiotherapy Versus Image-Guided Intensity Modulated External Beam Radiotherapy in

B Rai1, T Dey1, N Ballari2

  • 1Dept of Radiotherapy and Oncology, PGIMER, Chandigarh, India.

Clinical Oncology (Royal College of Radiologists (Great Britain))
|August 29, 2024
PubMed
Summary
This summary is machine-generated.

Intensity-modulated radiation therapy (IMRT) significantly reduces acute toxicities for locally advanced cervical cancer patients. Image-guided IMRT (IG-IMRT) with patient-specific margins improves organ-at-risk sparing without compromising tumor control.

Keywords:
3DCRTIGRTcervixpatient-specific ITV

More Related Videos

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

495
Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization
09:49

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Published on: December 2, 2013

10.3K

Related Experiment Videos

Last Updated: Jun 14, 2025

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.1K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

495
Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization
09:49

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Published on: December 2, 2013

10.3K

Area of Science:

  • Radiation Oncology
  • Gynecologic Oncology
  • Medical Physics

Background:

  • Standard treatment for locally advanced cervical carcinoma involves chemoradiation and brachytherapy.
  • Reducing acute and late toxicities is a key concern in cervical cancer treatment.
  • Intensity-modulated radiation therapy (IMRT) shows promise in lowering treatment-related toxicities.

Purpose of the Study:

  • To compare 3D conformal radiation therapy (3DCRT) with image-guided IMRT (IG-IMRT) in treating cervical cancer.
  • To evaluate tumor control and organ-at-risk (OAR) toxicities between 3DCRT and IG-IMRT.
  • To assess the impact of patient-specific margins in IG-IMRT for cervical cancer.

Main Methods:

  • A prospective phase III randomized controlled study was conducted.
  • Patients with stage II-IIIB cervical squamous cell carcinoma without pelvic lymph node involvement were included.
  • IG-IMRT involved additional scans for personalized internal target volume (ITV) margins, while 3DCRT used standard margins.

Main Results:

  • Eighty-nine patients received 3DCRT and 84 received IG-IMRT; baseline characteristics were comparable.
  • IG-IMRT demonstrated significantly better dosimetric parameters for OARs.
  • Acute toxicities, including dermatitis and gastrointestinal/genitourinary issues, were significantly lower in the IG-IMRT group.
  • Local, pelvic, and distant tumor control rates were similar between both treatment arms.

Conclusions:

  • Image-guided IMRT (IG-IMRT) with patient-specific margins effectively reduces acute OAR toxicities in cervical cancer patients.
  • IG-IMRT offers an improved safety profile compared to 3DCRT.
  • Tumor control is maintained when using IG-IMRT with personalized margins.