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[Repeated coronarographies in 122 medically treated patients]
Archives Des Maladies Du Coeur Et Des Vaisseaux
|February 1, 1985
Summary
Repeat coronary angiography in 122 patients revealed significant coronary lesion progression in over half. Worsened left ventricular function was more common in patients with advanced coronary artery disease.
Area of Science:
- Cardiology
- Interventional Cardiology
Background:
- Coronary artery disease (CAD) is a leading cause of mortality worldwide.
- Understanding the natural progression of CAD is crucial for effective patient management and treatment strategies.
Purpose of the Study:
- To evaluate changes in coronary angiography findings over time in patients with established CAD.
- To identify factors associated with disease progression or regression.
Main Methods:
- Retrospective analysis of 122 patients undergoing repeat coronary angiography.
- Exclusion of patients with normal coronary arteries.
- Categorization of patients into groups based on angiographic findings: unchanged, regression, or progression of coronary lesions.
Main Results:
- Over half of patients (56.6%) showed progression of coronary lesions.
- A smaller proportion experienced regression of lesions (9.8%), including recanalization in 3 cases.
- Worsening of left ventricular function was significantly more prevalent in patients with progressing CAD (21.7%) compared to those with stable or regressed disease (5.6%).
Conclusions:
- Coronary artery disease commonly progresses over time, as evidenced by repeat angiography.
- Progression of coronary lesions is associated with a higher incidence of left ventricular dysfunction.
- These findings underscore the importance of ongoing monitoring and aggressive management of CAD.