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Updated: Jun 14, 2025

Environmental Modulations of the Number of Midbrain Dopamine Neurons in Adult Mice
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Published on: January 20, 2015

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Dynorphin modulates motivation through a pallido-amygdala cholinergic circuit

Qingtao Sun, Mingzhe Liu, Wuqiang Guan

    Biorxiv : the Preprint Server for Biology
    |August 30, 2024
    PubMed
    Summary

    Dynorphin modulates motivation by controlling acetylcholine release in mice. This opioid peptide acts on a disinhibitory circuit, influencing reward-seeking behaviors and preventing perseverant actions.

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