Case Report: C-reactive protein apheresis in non-ST-elevation ACS-case series from the C-reactive protein apheresis
J Torzewski1, S Mattecka2, F Esposito3
1Cardiovascular Center Oberallgaeu-Kempten, Clinic Association Allgaeu, Kempten, Germany.
Insights
C-reactive protein (CRP) apheresis, a novel treatment, was successfully applied for the first time in non-ST-elevation acute coronary syndrome (NSTE-ACS) patients. This innovative therapy was well-tolerated and showed promising results in managing high CRP levels in these individuals.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Inflammation Biomarkers
Background:
- C-reactive protein (CRP) is a key inflammatory marker in acute coronary syndromes.
- CRP apheresis has demonstrated efficacy in ST-elevation myocardial infarction and cardiogenic shock.
- The role of CRP apheresis in non-ST-elevation acute coronary syndrome (NSTE-ACS) remains largely unexplored.
Abstract:
C-reactive protein (CRP) apheresis has been introduced in ST-elevation myocardial infarction and cardiogenic shock. Here, we describe a first-in-man application in non-ST-elevation acute coronary syndrome (NSTE-ACS). Seven NSTE-ACS patients with high CRP levels (range 14.2-154 mg/L) were treated with CRP apheresis. Treatment was well-tolerated. Patients were discharged in good clinical condition.
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